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Splenectomy Haematological

Splenectomy is a standard and effective treatment modality for patients with recurrent, refractory, or chronic diseases for which drug treatment fails or is unable to cure [2]. After the failure of medical therapy, splenectomy is indicated for the red blood cells disorders and a variety of thrombocytopenic disorders.

Splenectomy is reported to increase the haemoglobin level in patients with haemoglobin H Constant Spring (HbH CS) disease; however, its impact on iron burden and the underlying mechanism remains unclear.